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Why are brunners glands important?

Why are brunners glands important?

Brunner’s gland, which was accurately described by Brunner in 1688, is a gland in the submucosa of the duodenum (1), which has a main physiological function of secreting an alkaline-based mucus to protect the duodenal lining from the acid secreted in the stomach.

Where are brunners glands mainly found?

Brunner’s glands are unique to mammalian species and in eutherians are confined primarily to the submucosa of the proximal duodenum. In the majority of species examined, they begin at the gastrointestinal junction and extend for variable distances distally in the wall of the proximal small intestine.

Are Brunner’s glands exocrine?

Exocrine glands have ducts – and they secrete onto a surface: examples of exocrine glands are: sebaceous and sweat glands (in the skin), salivary glands (oral), Brunner’s glands.

What do you mean by Brunner’s gland?

Medical Definition of Brunner’s gland : any of the compound racemose glands in the submucous layer of the duodenum that secrete alkaline mucus and a potent proteolytic enzyme. — called also duodenal gland, gland of Brunner.

Where are crypts of Lieberkuhn located?

In histology, an intestinal gland (also crypt of Lieberkühn and intestinal crypt) is a gland found in between villi in the intestinal epithelium lining of the small intestine and large intestine (or colon).

What are the functions of the Brunner glands?

Brunner glands. THIS IS A DIRECTORY PAGE. Britannica does not currently have an article on this topic. In small intestine Secretions from Brunner glands, in the submucosa of the duodenum, function principally to protect the intestinal walls from gastric juices.

How are Brunner’s glands related to the duodenum?

Brunner’s glands. They also secrete urogastrone, which inhibits parietal and chief cells of the stomach from secreting acid and their digestive enzymes. [citation needed] This is another form of protection for the duodenum. They are the distinguishing feature of the duodenum, and are named for the Swiss physician who first described them,…

How is mucus fluid secreted from Brunner’s glands?

Secretion of mucus fluid from Brunner’s glands and the epithelium clearly has an important role in normal duodenal function. However, the pathway for the water component of this secretion is so far undetermined.

How are Brunner’s glands related to the lamina propria?

Occasionally, Brunner’s glands coalesce and extensively involve the lamina propria, creating small sessile, polypoid excrescences or imparting a nodular appearance to the mucosal surface (Fig. 18-1 ).