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Which indicate risks of Plummer-Vinson syndrome?
Since Plummer-Vinson syndrome is associated with an increased risk of squamous cell carcinoma of the pharynx and the esophagus, the patients should be followed closely.
Is Plummer-Vinson syndrome premalignant?
Plummer Vinson syndrome, (also known as Patterson Kelly brown syndrome, sideropenic dysphagia, hysterical dysphagia) is a premalignant condition, in which the patient has iron deficiency anemia, dysphagia and possibly a post-cricoid web that can predispose to malignant change.
What is another name for Plummer-Vinson syndrome?
The association of postcricoid dysphagia, upper esophageal webs, and iron deficiency anemia is known as Plummer-Vinson syndrome (PVS) in the United States and Paterson-Brown Kelly syndrome in the United Kingdom.
What causes koilonychia?
Spoon nails (koilonychia) are soft nails that look scooped out. The depression usually is large enough to hold a drop of liquid. Often, spoon nails are a sign of iron deficiency anemia or a liver condition known as hemochromatosis, in which your body absorbs too much iron from the food you eat.
Can anemia affect your throat?
Difficulty in swallowing or dysphagia is a common symptom. Esophageal webs are an infrequent cause of dysphagia. These have been found to occur in association with iron deficiency anemia (IDA) and dysphagia.
Why does iron deficiency cause Koilonychia?
Koilonychia occurs in 5.4% of the patients with iron deficiency. It is thought to occur due to the upward deformation of lateral and distal portions of pliable iron deficient nail plates under mechanical pressure. Nail matrix changes due to blood flow abnormalities was also proposed as a pathomechanism.
What are the symptoms of Plummer Vinson syndrome?
Esophageal webs in the setting of iron deficiency anemia. This is seen in Plummer-Vinson syndrome. This syndrome usually has: dysphagia. esophageal web. atrophic glossitis (inflammation of tongue) and/or cheilitis (inflammation around the lips/mouth) iron deficiency anemia.
Where are esophageal webs found in Plummer Vinson syndrome?
Given her dysphagia, esophageal webs are highest on the differential. A barium esophagram (figure below) will confirm the diagnosis. The esophageal webs of Plummer-Vinson syndrome are usually in the upper esophagus and more common in women.
Where are Schatzki rings found in Plummer Vinson syndrome?
Esophageal webs in Plummer–Vinson syndrome are found at upper end of esophagus (post cricoid region) and Schatzki rings may be found at the lower end of esophagus. The Following clinical presentations may be used in the diagnosis of this condition. The following tests are helpful in the diagnosis of Plummer–Vinson syndrome.
What causes laryngeal crepitus in Plummer Vinson syndrome?
It may also present as a post-cricoid malignancy which can be detected by loss of laryngeal crepitus. Laryngeal crepitus is found normally and is produced because the cricoid cartilage rubs against the vertebrae. The cause of Plummer–Vinson syndrome is unknown; however, genetic factors and nutritional deficiencies may play a role.