Contents
What are halogenated Anaesthetics?
OVERVIEW. The halogenated inhalational anesthetics have been linked to idiosyncratic liver injury for more than 50 years. These agents induce anesthesia by blocking CNS neurotransmission, although the exact mechanism of action is unknown. They are currently the most commonly used inhalational anesthetics in surgery.
What are fluorinated anesthetics?
An inhalational anesthetic is a chemical compound possessing general anesthetic properties that can be delivered via inhalation. They are administered through a face mask, laryngeal mask airway or tracheal tube connected to an anesthetic vaporiser and an anesthetic delivery system.
What are the halogenated gases?
All inhalation anesthetics in current clinical use are halogenated ethers, except for halothane (which is a halogenated hydrocarbon or haloalkane), nitrous oxide, and xenon. These other gases always include oxygen or air, but may also include other gases such as nitrous oxide or helium.
What are halogenated liquids?
Halogenated hydrocarbons, also known as halocarbons, are hydrocarbon compounds in which at least one hydrogen atom is replaced by a halogen (Group VII A of the Periodic Table) atom, such as fluorine, chlorine, or bromine.
What is meant by halogenated?
Halogenation is a type of chemical reaction where hydrogen atoms are replaced by halogen atoms in a molecule. The end product of halogenation is a compound that has distinct properties that are different from the starting compound.
What is halothane used for?
Fluothane (halothane) produces moderate muscular relaxation. Muscle relaxants are used as adjuncts in order to maintain lighter levels of anesthesia. Fluothane (halothane) augments the action of nondepolarizing relaxants and ganglionic-blocking agents. Fluothane (halothane) is a potent uterine relaxant.
Which gas is used as anesthetic?
Anesthetic gases (nitrous oxide, halothane, isoflurane, desflurane, sevoflurane), also known as inhaled anesthetics, are administered as primary therapy for preoperative sedation and adjunctive anesthesia maintenance to intravenous (IV) anesthetic agents (i.e., midazolam, propofol) in the perioperative setting.
What is the difference between halogenated and non halogenated?
A nonhalogenated compound is one which does not have a halogen (e.g., fluorine, chlorine, bromine, or iodine) attached to it. The vendor of the technology being evaluated must be informed whether the compounds to be treated are nonhalogenated or halogenated.
Why are halogenated anesthetics used in surgery?
One of the principal goals of general anesthesia is to prevent patients from feeling pain during surgery. Halogenated anesthetics, such as sevoflurane and desflurane, are typically administered in combination with nitrous oxide to produce surgical levels of anesthesia.
Which is the most studied halogenated ether anesthetic?
THE ETHER ANESTHETICS – ISOFLURANE The prototypical ether anesthetic in use today is isoflurane, and this has been the most studied of these agents in recent years. The available evidence suggests that the molecular pharmacology of isoflurane is representative of that of the other halogenated ethers.
How many healthcare workers are exposed to halogenated anesthetic gases?
More than 250,000 healthcare workers may be exposed to WAGs and are at risk of developing adverse health effects. Acute exposure to halogenated anesthetics can cause 1: Acute exposure to nitrous oxide can cause 4: Chronic nitrous oxide exposure in healthcare workers has been linked to 4,5:
What kind of anesthetic gases are used in surgery?
Halogenated anesthetics, such as sevoflurane and desflurane, are typically administered in combination with nitrous oxide to produce surgical levels of anesthesia. Anesthetic gases and vapors that leak into the surrounding room are considered waste anesthetic gases (WAGs).