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What is chemical incompatibility pharmaceutics?
Chemical Incompatibility: Reaction between two or more substances which lead to change in chemical properties of pharmaceutical dosage form.
What is the example of chemical incompatibility?
Appendix 3: Examples of Incompatible Chemicals
Chemical | Incompatible with |
---|---|
acetic acid | chromic acid, nitric acid, perchloric acid, peroxides, permanganates |
acetic anhydride | Hydroxyl-containing compounds such as ethylene glycol and perchloric acid |
acetylene | chlorine, bromine, copper, fluorine, silver, mercury |
What is tolerated chemical incompatibility?
A ) Tolerated : In tolerated incompatibilities,the chemical interaction can be minimised by changing the order of mixing or mixing the solutions in dilute forms but no. alteration is made in the formulation.
What is incompatibility and its types?
Incompatibility is defined as a change resulting and an undesirable product is formed, which may affect the safety, efficacy, appearance and stability of the pharmaceutical product. It is of three types. It includes physical, chemical and therapeutic incompatibilities.
What are the types of incompatibility?
Types of Incompatibility 1. Therapeutic incompatibility 2. Physical incompatibility 3. Chemical incompatibility Vakratunda Foundation, Akluj.
What is physical incompatibility?
Physical Incompatibility • Definition Interaction between two or more substances which lead to change in color, odor, taste, viscosity and morphology. • It is also called pharmaceutical incompatibilities.
How many types of chemical incompatibility are there?
3. Types of Incompatibility 1. Therapeutic incompatibility 2. Physical incompatibility 3.
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Which is the best definition of chemical incompatibility?
1. The quality of being incompatible. 2. A means of classifying bacterial plasmids; two plasmids are incompatible if they cannot coexist in one host cell. Transfusion medicine See Transfusion reaction. See ABO incompatibility, Rh incompatibility. 1. The quality of being incompatible. 2.
What causes chemical incompatibility when mixing two drugs?
Also know, what causes chemical incompatibility? Chemical incompatibility occurs when mixing two drugs changes the potency of their active ingredients. A drug that loses more than 10% of its potency when mixed with another drug is considered incompatible with that drug. Also, what is pharmaceutical incompatibility?
What are the 3 types of incompatibilities in medicine?
Abstract 1 Physical incompatibilities 2 Chemical incompatibilities 3 Therapeutic incompatibilities
Which is chemical incompatible with copper or chlorine?
What is chemical incompatibility? Chemical Incompatible with Copper hydrogen peroxide Hydrocarbons bromine, chlorine, peroxides Hydrogen peroxide combustible materials, copper, iron, mos Iodine Ammonia