What is the purpose of the aspirin synthesis lab?

What is the purpose of the aspirin synthesis lab?

The purpose of this lab was to synthesize Aspirin and measure the synthesized Aspirin’s purity. By calculating the theoretical yield based on the original amount of Salicylic acid, one could determine the actual yield percentage of the reaction.

What is the importance of acetylsalicylic acid?

Acetylsalicylic acid (ASA) is effective in preventing strokes, heart attacks and vascular-related events associated with cardiovascular disease (CVD). Notwithstanding, many patients suffer recurrent events while on ASA therapy.

What was the purpose of Recrystallizing your aspirin?

Recrystallisation of Aspirin. After the aspirin is prepared, the crude product is relatively impure and needs to be purified by Recrystallisation. The solvent that is used for this is ethanol and water.

What is the purpose of adding a few drops of sulfuric acid to the reaction used to synthesize aspirin?

Making aspirin In this case just a few drops of sulphuric acid added to the mixture means that there are some free positive hydrogen ions in the solution which can bind to the ethanoic anhydride. This makes it more active and speeds up the reaction. To ensure the reaction goes as quickly as possible we have to heat it.

What type of reaction is the synthesis of aspirin?

esterification reaction
The synthesis of aspirin is known in organic chemistry as an esterification reaction. This is a substitution reaction in which an alcohol (the –OH group in salicylic acid) reacts with acetic anhydride to form an ester, aspirin.

Why is water added in aspirin synthesis?

The mixture is heated to form the acetylsalicylic acid (C9H8O4) and acetic acid (C2H4O2). After the reaction takes place, water is added to destroy the excess acetic anhydride and cause the product to crystallize. The aspirin is then collected, purified by recrystallization, and its melting temperature measured.

Is acetylsalicylic acid a blood thinner?

About low-dose aspirin Daily low-dose aspirin is a blood thinning medicine. Aspirin is also known as acetylsalicylic acid. Low-dose aspirin helps to prevent heart attacks and strokes in people at high risk of them.

How does aspirin work in the body?

Aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen and indomethacin work by inhibiting an enzyme that produces prostaglandins–hormone-like messenger molecules that trigger many processes in the body, including inflammation.

Why is ethanol used in aspirin?

The aspirin molecule is made up of a benzene ring, a carboxyl group, and an ester. It has both polar and non-polar components. Thus, the affinity of water (very polar) for this compound is not as great as the affinity of water for itself. Thus, aspirin is more soluble in ethanol than in water.

How is acetylsalicyclic acid used in medicine?

As we know acetylsalicyclic acid is a drug that is widely used as an antipyretic agent that is to reduce fever ,as an analgesic agent which is to reduce pain and as an anti-inflammatory.Chemically acetylsalicyclic acid is an ester.Esters are the products of the reaction of acids with alcohols ,…

How is acetylsalicylic acid prepared in the esterification reaction?

The preparation consists of an esterification reaction catalyzed by acid (H2SO4 or H3PO4), where salicylic acid treated with acetic anhydride gives acetylsalicylic acid (aspirin). How do you purify synthesized aspirin?

How long does it take to make acetylsalicylic acid?

The second plate was used to compare the initial reactants and the reaction after 10 minutes of heating. The reaction mixture of salicylic acid, acetic anhydride, and phosphoric acid was mixed thoroughly and heated in a water bath at 90 degrees Celsius for 5 minutes.

How to make acetylsalicylic acid ( aspirin ) lab 1?

Next, 8mL of Acetic Anhydride was obtained using a 10mL graduated cylinder. 2.0mL Acetic Anhydride was poured into each test tube. 0.20 grams of Sodium Acetate was obtained and placed in a weigh boat.