Contents
What makes a molecule more acidic or basic?
In general, the strength of an acid in an organic compound is directly proportional to the stability of the acid’s conjugate base. In other words, an acid that has a more stable conjugate base will be more acidic than an acid that has a less stable conjugate base.
How do you know which solutions are acidic?
A solution is acidic if the concentration of hydrogen ions in the solution is greater than the concentration of hydroxide ions in the solution. example: The concentration of hydrogen ions in a solution is 0.025 mol L-1 and the concentration of hydroxide ions in the same solution is 0.012 mol L-1.
How do you know which functional group is more acidic?
A carboxylic acid is the most common acidic functional group found in drug molecules. The acidic hydrogen atom has been highlighted with a box below. The resulting anion (i.e., negatively charged species) is stabilized by resonance delocalization or the sharing of the negative charge between the two oxygen atoms.
How do you know if a salt is acidic?
We determine whether the hydrolyzable ion is acidic or basic by comparing the Ka and Kb values for the ion; if Ka > Kb, the ion will be acidic, whereas if Kb > Ka, the ion will be basic. Anilinium chloride: Anilinium chloride is an example of an acid salt.
Is SH stronger than Oh?
The thiol is more acidic because the sulfur atom is larger than the oxygen atom. This has two effects. (1) it makes the S-H bond longer and weaker than the O-H bond and so favours loss of H+.
How do you know which hydrogen is most acidic?
How do we know which proton is the most acidic in a molecule (such as acetic acid) that contains more than one type of proton? Remember that the higher the degree of positive character on the proton, the more acidic it is. Examination of a pKa table reveals some trends for acidic protons.
How do we know which proton is the most acidic in a molecule?
Why are some h more acidic than others?
Every H in an Organic molecule is potentially acidic it’s just that some are more acidic than others. There are two important factors: 1. the bond polarity taken together with the bond strength.
How to identify acidic hydrogen in an organic compound?
a heteroatom (such as sulfur) that forms an inorganic oxyacid, and typically has one or more other oxygens attached to it. That should cover 99.9% of the cases. Every H in an Organic molecule is potentially acidic it’s just that some are more acidic than others.
Why are acids more acidic at the periodic table?
Therefore, as we go down the periodic table, we tend to get to more acidic compounds because the conjugate base is more stable. The pKa for ethanethiol, if I just look that up over here, we’ve got a 10.6 so quite a bit…